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Anaplasma phagocytophilum PCR testing for cats detects this tick-borne pathogen that causes feline granulocytic anaplasmosis. This molecular test identifies the bacterium's DNA in feline blood samples, allowing for diagnosis of this often-underdiagnosed infection that can cause fever, lethargy, and cytopenias in cats and has zoonotic potential, making accurate identification important for both feline health and public health considerations.
Feline-Specific Anaplasma DetectionZoonotic Pathogen AssessmentCo-infection ScreeningEarly Infection IdentificationNeutrophil-Targeting Pathogen Diagnosis.png)
Anaplasma phagocytophilum is a gram-negative intracellular bacterium transmitted primarily by Ixodes species ticks that can infect cats, dogs, humans, and other mammals. In cats, it causes feline granulocytic anaplasmosis, which is often subclinical but can manifest as fever, lethargy, anorexia, and less commonly, lameness or neurological signs. Laboratory abnormalities may include thrombocytopenia, mild anemia, and leukopenia. While feline anaplasmosis is less documented than canine cases, recent studies suggest cats may serve as reservoir hosts, highlighting the importance of testing, particularly in regions with endemic tick populations.
Clinical Significance of Feline A. phagocytophilum Testing
Underdiagnosed Infection: Frequently overlooked in feline medicine despite prevalence.
One Health Context: Zoonotic potential makes detection important for public health.
Co-infections: Often occurs with other tick-borne diseases affecting clinical presentation.
Subtle Presentation: May cause vague clinical signs easily attributed to other conditions.
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